1xyu

Solution NMR

Solution structure of the sheep prion protein with polymorphism H168

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 13.1 KDa
Source organism: Ovis aries
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P23907 (Residues: 124-234; Coverage: 48%)
Gene names: PRNP, PRP, SIP
Structure domains: Prion/Doppel protein, beta-ribbon domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21