X-ray diffraction
2.8Å resolution

K185N mutated S-adenosylhomocysteine hydrolase


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Adenosylhomocysteinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 431 amino acids
Theoretical weight: 47.45 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
  • Canonical: P10760 (Residues: 2-432; Coverage: 100%)
Gene name: Ahcy
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand NAD 4 x NAD
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P21
Unit cell:
a: 90.34Å b: 109.37Å c: 104.07Å
α: 90° β: 115.5° γ: 90°
R R work R free
0.226 0.225 0.286
Expression system: Escherichia coli