X-ray diffraction
1.9Å resolution

1.9 angstrom resolution structure of human glutathione S-transferase M1A-1A complexed with glutathione


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glutathione S-transferase Mu 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 218 amino acids
Theoretical weight: 25.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P09488 (Residues: 1-218; Coverage: 100%)
Gene names: GST1, GSTM1
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand GSH 4 x GSH
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 55.97Å b: 84.38Å c: 212.18Å
α: 90° β: 90° γ: 90°
R R work R free
0.24 0.227 0.247
Expression system: Escherichia coli BL21(DE3)