X-ray diffraction
2.8Å resolution

The 2.8 A structure of a tumour suppressing serpin


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Serpin B5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 380 amino acids
Theoretical weight: 42.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P36952 (Residues: 1-375; Coverage: 100%)
Gene names: PI5, SERPINB5
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P212121
Unit cell:
a: 53.54Å b: 100.48Å c: 136.61Å
α: 90° β: 90° γ: 90°
R R work R free
0.224 0.221 0.286
Expression system: Escherichia coli BL21