› 1xsf

Solution NMR

Solution structure of a resuscitation promoting factor domain from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb1xsf/pdb
PDB entry 1xsf coloured by chain, ensemble of 30 models, front view.
PDB entry 1xsf coloured by chain, ensemble of 30 models, side view.
PDB entry 1xsf coloured by chain, ensemble of 30 models, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes.
Cohen-Gonsaud M, Barthe P, Bagnéris C, Henderson B, Ward J, Roumestand C, Keep NH
Nat Struct Mol Biol 12 270-3 (2005)
PMID: 15723078

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161450 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Resuscitation-promoting factor RpfB Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 11.36 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WG29 (Residues: 255-362; Coverage: 32%)
Gene names: MTC1237.26, Rv1009, rpfB
Sequence domains: Transglycosylase-like domain
Structure domains: Lysozyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics in explicit solvent
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

33 review citations

Mycobacterium tuberculosis: success through dormancy.
Gengenbacher et al. (2012)
32 more

4 mentions without citation

Solution NMR Studies of Mycobacterium tuberculosis Proteins for Antibiotic Target Discovery.
Kim et al. (2017)
3 more