X-ray diffraction
2Å resolution

Tyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine


Function and Biology Details

Reaction catalysed:
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr)
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Tyrosine--tRNA ligase Chain: A
Molecule details ›
Chain: A
Length: 322 amino acids
Theoretical weight: 36.07 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
  • Canonical: P0AGJ9 (Residues: 1-322; Coverage: 76%)
Gene names: JW1629, b1637, tyrS
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32B2
Spacegroup: P3121
Unit cell:
a: 82.82Å b: 82.82Å c: 93.49Å
α: 90° β: 90° γ: 120°
R R work R free
0.195 0.191 0.22
Expression system: Escherichia coli