X-ray diffraction
2.5Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
Non-polymer only tetramer (preferred)
Non-polymer only octamer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Amyloid-beta A4 precursor protein-binding family A member 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 172 amino acids
Theoretical weight: 19.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q02410 (Residues: 453-623; Coverage: 20%)
Gene names: APBA1, MINT1, X11
Sequence domains: Phosphotyrosine interaction domain (PTB/PID)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
C31 Chains: C, D
Molecule details ›
Chains: C, D
Length: 13 amino acids
Theoretical weight: 1.64 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P05067 (Residues: 754-766; Coverage: 2%)
Gene names: A4, AD1, APP

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P41212
Unit cell:
a: 74.6Å b: 74.6Å c: 155.4Å
α: 90° β: 90° γ: 90°
R R work R free
0.214 0.214 0.304
Expression systems:
  • Escherichia coli
  • Not provided