1wr6

X-ray diffraction
2.6Å resolution

Crystal structure of GGA3 GAT domain in complex with ubiquitin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ADP-ribosylation factor-binding protein GGA3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 111 amino acids
Theoretical weight: 12.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NZ52 (Residues: 209-319; Coverage: 15%)
Gene names: GGA3, KIAA0154
Sequence domains: GAT domain
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Ubiquitin Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 76 amino acids
Theoretical weight: 8.58 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P0CH28 (Residues: 609-684; Coverage: 11%)
Gene name: UBC
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A, PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P212121
Unit cell:
a: 56.026Å b: 113.628Å c: 114.703Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.221 0.29
Expression system: Escherichia coli