1uon

Electron Microscopy
7.6Å resolution

REOVIRUS POLYMERASE LAMBDA-3 LOCALIZED BY ELECTRON CRYOMICROSCOPY OF VIRIONS AT 7.6-A RESOLUTION

Released:

Function and Biology Details

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
Macromolecules (3 distinct):
RNA-directed RNA polymerase Chain: A
Molecule details ›
Chain: A
Length: 1267 amino acids
Theoretical weight: 142.42 KDa
Source organism: Reovirus sp.
UniProt:
  • Canonical: Q8V1A3 (Residues: 1-121; Coverage: 100%)
Sequence domains: Reovirus RNA-dependent RNA polymerase lambda 3
5'-R(*GP*GP*GP*GP*GP*)-3' Chain: B
Molecule details ›
Chain: B
Length: 5 nucleotides
Theoretical weight: 1.68 KDa
Source organism: synthetic construct
Expression system: Not provided
5'-R(*UP*AP*GP*CP*CP*CP*CP*CP*)-3' Chain: C
Molecule details ›
Chain: C
Length: 8 nucleotides
Theoretical weight: 2.46 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 7.6Å
Expression system: Not provided