1udh

X-ray diffraction
1.75Å resolution

THE STRUCTURAL BASIS OF SPECIFIC BASE EXCISION REPAIR BY URACIL-DNA GLYCOSYLASE

Released:

Function and Biology Details

Reaction catalysed:
Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uracil-DNA glycosylase Chain: A
Molecule details ›
Chain: A
Length: 244 amino acids
Theoretical weight: 27.37 KDa
Source organism: Human alphaherpesvirus 1 strain 17
UniProt:
  • Canonical: P10186 (Residues: 91-334; Coverage: 73%)
Gene name: UL2
Sequence domains: Uracil DNA glycosylase superfamily
Structure domains: Uracil-DNA glycosylase-like domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P31
Unit cell:
a: 65.14Å b: 65.14Å c: 49.16Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.191 0.191 0.237