X-ray diffraction
2.38Å resolution

Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879)


Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin Chain: A
Molecule details ›
Chain: A
Length: 280 amino acids
Theoretical weight: 31.33 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P12003 (Residues: 1-259; Coverage: 23%)
Gene names: VCL, VINC1
Structure domains: Alpha-catenin/vinculin-like
Talin-1 Chain: B
Molecule details ›
Chain: B
Length: 31 amino acids
Theoretical weight: 3.13 KDa
Source organism: Gallus gallus
Expression system: Not provided
  • Canonical: P54939 (Residues: 849-879; Coverage: 1%)
Gene names: TLN, TLN1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21212
Unit cell:
a: 52.122Å b: 69.154Å c: 96.162Å
α: 90° β: 90° γ: 90°
R R work R free
0.246 0.242 0.322
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided