X-ray diffraction
2.2Å resolution

Crystal Structure of human RANTES mutant 44-AANA-47


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
C-C motif chemokine 5 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 68 amino acids
Theoretical weight: 7.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P13501 (Residues: 24-91; Coverage: 100%)
Gene names: CCL5, D17S136E, SCYA5
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR571
Spacegroup: P21
Unit cell:
a: 22.818Å b: 80.475Å c: 65.442Å
α: 90° β: 94.52° γ: 90°
R R work R free
0.222 0.222 0.306
Expression system: Escherichia coli BL21(DE3)