1ty4

X-ray diffraction
2.2Å resolution

Crystal structure of a CED-9/EGL-1 complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
Non-polymer only tetramer
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apoptosis regulator ced-9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 170 amino acids
Theoretical weight: 20.32 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P41958 (Residues: 68-237; Coverage: 61%)
Gene names: T07C4.8, ced-9
Sequence domains:
Structure domains: Blc2-like
Programmed cell death activator egl-1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 57 amino acids
Theoretical weight: 6.45 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O61667 (Residues: 46-102; Coverage: 54%)
Gene names: F23B12.9, egl-1
Sequence domains: Programmed cell death activator EGL-1

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P43
Unit cell:
a: 93.713Å b: 93.713Å c: 57.447Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.212 0.235
Expression system: Escherichia coli BL21(DE3)