PDBe 1t1f

X-ray diffraction
2.75Å resolution

Crystal Structure of Native Antithrombin in its Monomeric Form

Released:

Function and Biology Details

Biochemical function:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antithrombin-III Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 432 amino acids
Theoretical weight: 49.09 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01008 (Residues: 33-464; Coverage: 100%)
Gene names: AT3, PRO0309, SERPINC1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 153.83Å b: 43.71Å c: 153.93Å
α: 90° β: 120.01° γ: 90°
R-values:
R R work R free
0.225 0.225 0.239
Expression system: Cricetulus griseus