› 1t1d

X-ray diffraction
1.51Å resolution

CRYSTAL STRUCTURE OF THE TETRAMERIZATION DOMAIN OF THE SHAKER POTASSIUM CHANNEL

Released:
DOI: 10.2210/pdb1t1d/pdb
PDB entry 1t1d coloured by chain, front view.
PDB entry 1t1d coloured by chain, side view.
PDB entry 1t1d coloured by chain, top view.
Source organism: Aplysia californica
Primary publication:
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels.
Bixby KA, Nanao MH, Shen NV, Kreusch A, Bellamy H, Pfaffinger PJ, Choe S
Nat Struct Biol 6 38-43 (1999)
PMID: 9886290

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172616 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BTB domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 12.1 KDa
Source organism: Aplysia californica
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16968 (Residues: 66-165; Coverage: 19%)
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: I422
Unit cell:
a: 59.71Å b: 59.71Å c: 146.86Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.229 0.249
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

24 review citations

Molecular physiology and modulation of somatodendritic A-type potassium channels.
Jerng et al. (2004)
23 more

9 mentions without citation

Sequence and structural analysis of BTB domain proteins.
Stogios et al. (2005)
8 more