PDBe 1srn

X-ray diffraction
1.8Å resolution

THE REFINED CRYSTAL STRUCTURE OF A FULLY ACTIVE SEMISYNTHETIC RIBONUCLEASE AT 1.8 ANGSTROMS RESOLUTION

Released:
Source organism: Bos taurus

Function and Biology Details

Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 118 amino acids
Theoretical weight: 13.05 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P61823 (Residues: 27-144; Coverage: 95%)
Gene names: RNASE1, RNS1
Structure domains: Ribonuclease A-like domain
Ribonuclease pancreatic Chain: B
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.53 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P61823 (Residues: 137-150; Coverage: 11%)
Gene names: RNASE1, RNS1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 67.68Å b: 67.68Å c: 65.03Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 not available not available
Expression system: Not provided