› 1ruz

X-ray diffraction
2.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194354 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemagglutinin HA1 chain Chains: H, J, L
Molecule details ›
Chains: H, J, L
Length: 328 amino acids
Theoretical weight: 36.13 KDa
Source organism: Influenza A virus (A/South Carolina/1/1918(H1N1))
UniProt:
  • Canonical: Q9WFX3 (Residues: 14-341; Coverage: 59%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin HA2 chain Chains: I, K, M
Molecule details ›
Chains: I, K, M
Length: 160 amino acids
Theoretical weight: 18.21 KDa
Source organism: Influenza A virus (A/South Carolina/1/1918(H1N1))
UniProt:
  • Canonical: Q9WFX3 (Residues: 345-504; Coverage: 29%)
Gene name: HA
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

2 bound ligands:
Ligand NDG 9 x NDG
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P41212
Unit cell:
a: 171.461Å b: 171.461Å c: 153.445Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.248 0.289

Quick links

Citations

81 review citations

Cross-species virus transmission and the emergence of new epidemic diseases.
Parrish et al. (2008)
80 more

52 mentions without citation

Molecular basis of the structure and function of H1 hemagglutinin of influenza virus.
Sriwilaijaroen et al. (2012)
51 more