1rhg

X-ray diffraction
2.2Å resolution

THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS

Released:
Source organism: Homo sapiens
Primary publication:
The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors.
Proc. Natl. Acad. Sci. U.S.A. 90 5167-71 (1993)
PMID: 7685117

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Granulocyte colony-stimulating factor Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 174 amino acids
Theoretical weight: 18.69 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09919 (Residues: 31-207; Coverage: 98%)
  • Best match: P09919-2 (Residues: 31-204)
Gene names: C17orf33, CSF3, GCSF
Sequence domains: Granulocyte colony-stimulating factor
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 90.9Å b: 110.7Å c: 49.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 not available
Expression system: Not provided