PDBe 1qmb

X-ray diffraction
2.6Å resolution

Cleaved alpha-1-antitrypsin polymer

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-1-antitrypsin Chain: A
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 36.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01009 (Residues: 49-376; Coverage: 83%)
Gene names: AAT, PI, PRO0684, PRO2209, SERPINA1
Structure domains:
Short peptide from AAT Chain: B
Molecule details ›
Chain: B
Length: 42 amino acids
Theoretical weight: 4.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01009 (Residues: 377-418; Coverage: 11%)
Gene names: AAT, PI, PRO0684, PRO2209, SERPINA1
Structure domains: Serpins superfamily

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P3121
Unit cell:
a: 108.59Å b: 108.59Å c: 110.65Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.212 0.258
Expression system: Escherichia coli