X-ray diffraction
2.5Å resolution

Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex


Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Large T antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 25 amino acids
Theoretical weight: 2.69 KDa
Source organism: Macaca mulatta polyomavirus 1
Expression system: Not provided
  • Canonical: P03070 (Residues: 110-134; Coverage: 4%)
  • Best match: P03070-2 (Residues: 110-131)
Importin subunit alpha-1 Chain: C
Molecule details ›
Chain: C
Length: 466 amino acids
Theoretical weight: 50.46 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P52293 (Residues: 70-529; Coverage: 87%)
Gene names: Kpna2, Rch1
Sequence domains:
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 79.157Å b: 89.282Å c: 100.335Å
α: 90° β: 90° γ: 90°
R R work R free
0.202 0.202 0.233
Expression systems:
  • Not provided
  • Escherichia coli