› 1q0e

X-ray diffraction
1.15Å resolution

Atomic resolution (1.15 ) crystal structure of bovine copper, zinc superoxide dismutase

Released:
DOI: 10.2210/pdb1q0e/pdb
PDB entry 1q0e coloured by chain, front view.
PDB entry 1q0e coloured by chain, side view.
PDB entry 1q0e coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structure of fully reduced bovine copper zinc superoxide dismutase at 1.15 A.
Hough MA, Hasnain SS
Structure 11 937-46 (2003)
PMID: 12906825

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132499 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 15.6 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00442 (Residues: 2-152; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

2 bound ligands:
Ligand CU 2 x CU
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P212121
Unit cell:
a: 46.953Å b: 51.507Å c: 148.41Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.131 0.131 0.166

Quick links

Citations

6 review citations

Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis.
Valentine et al. (2005)
5 more

5 mentions without citation

Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database.
Tung et al. (2007)
4 more