› 1pq0

X-ray diffraction
2.2Å resolution

Crystal structure of mouse Bcl-xl

Released:
DOI: 10.2210/pdb1pq0/pdb
PDB entry 1pq0 coloured by chain, front view.
PDB entry 1pq0 coloured by chain, side view.
PDB entry 1pq0 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The structure of a Bcl-xL/Bim fragment complex: implications for Bim function.
Liu X, Dai S, Zhu Y, Marrack P, Kappler JW
Immunity 19 341-52 (2003)
PMID: 14499110

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179130 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bcl-2-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 196 amino acids
Theoretical weight: 22.06 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q64373 (Residues: 1-196; Coverage: 84%)
Gene names: Bcl2l, Bcl2l1, Bclx
Sequence domains:
Structure domains: Blc2-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P41212
Unit cell:
a: 63.61Å b: 63.61Å c: 109.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.217 0.243
Expression system: Trichoplusia ni

Quick links

Citations

60 review citations

The BCL-2 protein family: opposing activities that mediate cell death.
Youle et al. (2008)
59 more

13 mentions without citation

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane.
Luna-Vargas et al. (2016)
12 more