› 1pmp

X-ray diffraction
2.7Å resolution

CRYSTALLOGRAPHIC STUDIES ON A FAMILY OF CELLULAR LIPOPHILIC TRANSPORT PROTEINS. REFINEMENT OF P2 MYELIN PROTEIN AND THE STRUCTURE DETERMINATION AND REFINEMENT OF CELLULAR RETINOL-BINDING PROTEIN IN COMPLEX WITH ALL-TRANS-RETINOL

Released:
DOI: 10.2210/pdb1pmp/pdb
PDB entry 1pmp coloured by chain, front view.
PDB entry 1pmp coloured by chain, side view.
PDB entry 1pmp coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystallographic studies on a family of cellular lipophilic transport proteins. Refinement of P2 myelin protein and the structure determination and refinement of cellular retinol-binding protein in complex with all-trans-retinol.
Cowan SW, Newcomer ME, Jones TA
J Mol Biol 230 1225-46 (1993)
PMID: 7683727

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136049 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myelin P2 protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 131 amino acids
Theoretical weight: 14.84 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P02690 (Residues: 2-132; Coverage: 99%)
Gene name: PMP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand OLA 3 x OLA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 91.8Å b: 99.5Å c: 56.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.268 0.268 not available
Expression system: Not provided

Quick links

Citations

20 review citations

Retinoid-binding proteins: mediators of retinoid action.
Noy N. (2000)
19 more

9 mentions without citation

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets.
Furuhashi et al. (2008)
8 more