1pk6

X-ray diffraction
1.85Å resolution

Globular Head of the Complement System Protein C1q

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Complement C1q subcomponent subunit A Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.91 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02745 (Residues: 112-244; Coverage: 60%)
Gene name: C1QA
Sequence domains: C1q domain
Structure domains: Jelly Rolls
Complement C1q subcomponent subunit B Chain: B
Molecule details ›
Chain: B
Length: 132 amino acids
Theoretical weight: 15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02746 (Residues: 119-250; Coverage: 58%)
Gene name: C1QB
Sequence domains: C1q domain
Structure domains: Jelly Rolls
Complement C1q subcomponent subunit C Chain: C
Molecule details ›
Chain: C
Length: 129 amino acids
Theoretical weight: 14.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02747 (Residues: 117-245; Coverage: 59%)
Gene names: C1QC, C1QG
Sequence domains: C1q domain
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 80.182Å b: 53.222Å c: 90.88Å
α: 90° β: 112.32° γ: 90°
R-values:
R R work R free
0.201 0.199 0.239