X-ray diffraction
2.5Å resolution

Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex


Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histone-binding protein N1/N2 Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.48 KDa
Source organism: Mus musculus
Expression system: Not provided
  • Canonical: P06180 (Residues: 532-553; Coverage: 4%)
Importin subunit alpha-1 Chain: B
Molecule details ›
Chain: B
Length: 460 amino acids
Theoretical weight: 49.89 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P52293 (Residues: 70-529; Coverage: 87%)
Gene names: Kpna2, Rch1
Sequence domains:
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 78.92Å b: 89.769Å c: 101.042Å
α: 90° β: 90° γ: 90°
R R work R free
0.209 0.209 0.233
Expression systems:
  • Not provided
  • Escherichia coli