PDBe 1oyh

X-ray diffraction
2.62Å resolution

Crystal Structure of P13 Alanine Variant of Antithrombin

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Antithrombin-III Chain: I
Molecule details ›
Chain: I
Length: 432 amino acids
Theoretical weight: 49.03 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01008 (Residues: 33-464; Coverage: 100%)
Gene names: AT3, PRO0309, SERPINC1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Antithrombin-III Chain: L
Molecule details ›
Chain: L
Length: 432 amino acids
Theoretical weight: 49.1 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01008 (Residues: 33-464; Coverage: 100%)
Gene names: AT3, PRO0309, SERPINC1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 68.998Å b: 98.573Å c: 89.35Å
α: 90° β: 105.53° γ: 90°
R-values:
R R work R free
0.221 0.221 0.258
Expression system: Cricetulus griseus