PDBe 1ors

X-ray diffraction
1.9Å resolution

X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab

Released:
Source organisms:
Primary publication:
X-ray structure of a voltage-dependent K+ channel.
Nature 423 33-41 (2003)
PMID: 12721618

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Immunoglobulin kappa constant Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 23.41 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ig gamma-1 chain C region, membrane-bound form Chain: B
Molecule details ›
Chain: B
Length: 221 amino acids
Theoretical weight: 24.04 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01869 (Residues: 1-103; Coverage: 26%)
Gene names: Igh-4, Ighg1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Voltage-gated potassium channel Chain: C
Molecule details ›
Chain: C
Length: 132 amino acids
Theoretical weight: 14.63 KDa
Source organism: Aeropyrum pernix
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9YDF8 (Residues: 33-161; Coverage: 44%)
Gene name: APE_0955
Structure domains: Voltage-gated potassium channels. Chain C

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: C2
Unit cell:
a: 264.71Å b: 61.6Å c: 46.06Å
α: 90° β: 90.35° γ: 90°
R-values:
R R work R free
0.231 0.231 0.251
Expression system: Escherichia coli