› 1oqy

Solution NMR

Structure of the DNA repair protein hHR23a

Released:
DOI: 10.2210/pdb1oqy/pdb
PDB entry 1oqy coloured by chain, ensemble of 12 models, front view.
PDB entry 1oqy coloured by chain, ensemble of 12 models, side view.
PDB entry 1oqy coloured by chain, ensemble of 12 models, top view.
Source organism: Homo sapiens
Primary publication:
DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a.
Walters KJ, Lech PJ, Goh AM, Wang Q, Howley PM
Proc Natl Acad Sci U S A 100 12694-9 (2003)
PMID: 14557549

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157078 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UV excision repair protein RAD23 homolog A Chain: A
Molecule details ›
Chain: A
Length: 368 amino acids
Theoretical weight: 40.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54725 (Residues: 2-363; Coverage: 100%)
Gene name: RAD23A
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

24 review citations

Ubiquitin-binding domains.
Hicke et al. (2005)
23 more

9 mentions without citation

Every protagonist has a sidekick: Structural aspects of human xeroderma pigmentosum-binding proteins in nucleotide excision repair.
Feltes BC. (2021)
8 more