X-ray diffraction
1.7Å resolution

Crystal structure of the complex of the PDZ tandem of syntenin with an interleukin 5 receptor alpha peptide.


Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
Non-polymer only trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Syntenin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 166 amino acids
Theoretical weight: 18.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: O00560 (Residues: 113-273; Coverage: 54%)
Gene names: MDA9, SDCBP, SYCL
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Interleukin-5 receptor subunit alpha Chain: P
Molecule details ›
Chain: P
Length: 8 amino acids
Theoretical weight: 939 Da
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q01344 (Residues: 413-420; Coverage: 2%)
Gene names: IL5R, IL5RA

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: C2
Unit cell:
a: 101.485Å b: 48.172Å c: 74.996Å
α: 90° β: 120.24° γ: 90°
R R work R free
0.148 0.148 0.213
Expression systems:
  • Escherichia coli BL21
  • Not provided