X-ray diffraction
1.85Å resolution

Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide.


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Syntenin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 79 amino acids
Theoretical weight: 8.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: O00560 (Residues: 197-270; Coverage: 25%)
Gene names: MDA9, SDCBP, SYCL
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Syndecan-4 Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 6 amino acids
Theoretical weight: 744 Da
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P31431 (Residues: 193-198; Coverage: 3%)
Gene name: SDC4

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: C2
Unit cell:
a: 58.337Å b: 54.441Å c: 50.219Å
α: 90° β: 98.65° γ: 90°
R R work R free
0.175 0.175 0.226
Expression systems:
  • Escherichia coli BL21
  • Not provided