1obx

X-ray diffraction
1.35Å resolution

Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
Non-polymer only tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Syntenin-1 Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 8.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O00560 (Residues: 197-270; Coverage: 25%)
Gene names: MDA9, SDCBP, SYCL
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Interleukin-5 receptor subunit alpha Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 939 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q01344 (Residues: 413-420; Coverage: 2%)
Gene names: IL5R, IL5RA

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: C2221
Unit cell:
a: 53.723Å b: 55.978Å c: 51.094Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.176 0.212
Expression systems:
  • Escherichia coli BL21
  • Not provided