X-ray diffraction
1.5Å resolution

Crystal Structure of the Disabled-1 (Dab1) PTB domain-ApoER2 peptide complex


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Disabled homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 17.08 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P97318 (Residues: 23-174; Coverage: 26%)
Gene name: Dab1
Sequence domains: Phosphotyrosine interaction domain (PTB/PID)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Apolipoprotein E Receptor-2 peptide Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.26 KDa
Source organism: Mus musculus
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1, null
Spacegroup: P212121
Unit cell:
a: 36.247Å b: 45.724Å c: 90.124Å
α: 90° β: 90° γ: 90°
R R work R free
0.214 0.222 0.245
Expression systems:
  • Escherichia coli
  • Not provided