PDBe 1nq9

X-ray diffraction
2.6Å resolution

Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of antithrombin in a heparin-bound intermediate state.
Biochemistry 42 8712-9 (2003)
PMID: 12873131

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antithrombin-III Chains: I, L
Molecule details ›
Chains: I, L
Length: 432 amino acids
Theoretical weight: 49.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01008 (Residues: 33-464; Coverage: 100%)
Gene names: AT3, PRO0309, SERPINC1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P21
Unit cell:
a: 69.679Å b: 86.76Å c: 96.921Å
α: 90° β: 109.54° γ: 90°
R-values:
R R work R free
0.209 0.209 0.25