1nl1

X-ray diffraction
1.9Å resolution

BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM ION

Released:

Function and Biology Details

Reaction catalysed:
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Activation peptide fragment 1 Chain: A
Molecule details ›
Chain: A
Length: 147 amino acids
Theoretical weight: 16.97 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00735 (Residues: 44-190; Coverage: 25%)
Gene name: F2
Sequence domains:
Structure domains: Plasminogen Kringle 4

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P212121
Unit cell:
a: 39.188Å b: 53.443Å c: 128.173Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.219 0.253