X-ray diffraction
2.02Å resolution

2.0 A crystal structure of GDP-mannose dehydrogenase


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
GDP-mannose 6-dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 436 amino acids
Theoretical weight: 48.08 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P11759 (Residues: 1-436; Coverage: 100%)
Gene names: PA3540, algD
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand NAD 4 x NAD
2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43
Unit cell:
a: 82.497Å b: 82.497Å c: 310.173Å
α: 90° β: 90° γ: 90°
R R work R free
0.21 0.209 0.234
Expression system: Escherichia coli BL21(DE3)