1miz

X-ray diffraction
1.9Å resolution

Crystal structure of an integrin beta3-talin chimera

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin beta-3 Chain: A
Molecule details ›
Chain: A
Length: 9 amino acids
Theoretical weight: 959 Da
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05106 (Residues: 765-769; Coverage: 1%)
Gene names: GP3A, ITGB3
Talin-1 Chain: B
Molecule details ›
Chain: B
Length: 201 amino acids
Theoretical weight: 23.17 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54939 (Residues: 200-400; Coverage: 8%)
Gene names: TLN, TLN1
Sequence domains: FERM central domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 37.533Å b: 55.198Å c: 46.751Å
α: 90° β: 97.58° γ: 90°
R-values:
R R work R free
0.204 0.204 0.246
Expression system: Escherichia coli BL21(DE3)