› 1lxn

X-ray diffraction
2.3Å resolution

X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272

Released:
DOI: 10.2210/pdb1lxn/pdb
PDB entry 1lxn coloured by chain, front view.
PDB entry 1lxn coloured by chain, side view.
PDB entry 1lxn coloured by chain, top view.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Crystal structures of MTH1187 and its yeast ortholog YBL001c.
Tao X, Khayat R, Christendat D, Savchenko A, Xu X, Goldsmith-Fischman S, Honig B, Edwards A, Arrowsmith CH, Tong L
Proteins 52 478-80 (2003)
PMID: 12866058

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-127880 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UPF0045 protein MTH_1187 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 99 amino acids
Theoretical weight: 10.95 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O27255 (Residues: 1-99; Coverage: 100%)
Gene name: MTH_1187
Sequence domains: Thiamine-binding protein
Structure domains: Alpha-Beta Plaits

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A, APS BEAMLINE 19-BM
Spacegroup: P4132
Unit cell:
a: 175.365Å b: 175.365Å c: 175.365Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.216 0.245
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural proteomics: a tool for genome annotation.
Yakunin et al. (2004)
5 other articles

1 mention without citation

Towards functional characterization of archaeal genomic dark matter.
Makarova et al. (2019)