PDBe 1lx7

X-ray diffraction
2Å resolution

Structure of E. coli uridine phosphorylase at 2.0A

Released:
Source organism: Escherichia coli
Primary publication:
Structure of Escherichia coli uridine phosphorylase at 2.0 A.
Acta Crystallogr. D Biol. Crystallogr. 59 73-6 (2003)
PMID: 12499542

Function and Biology Details

Reaction catalysed:
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uridine phosphorylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 253 amino acids
Theoretical weight: 27.56 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P12758 (Residues: 1-253; Coverage: 100%)
Gene names: JW3808, b3831, udp
Sequence domains: Phosphorylase superfamily
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: R3
Unit cell:
a: 151.375Å b: 151.375Å c: 48.151Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.182 0.215
Expression system: Escherichia coli