PDBe 1lot

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF THE COMPLEX OF ACTIN WITH VITAMIN D-BINDING PROTEIN

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vitamin D-binding protein Chain: A
Molecule details ›
Chain: A
Length: 458 amino acids
Theoretical weight: 51.28 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02774 (Residues: 17-474; Coverage: 100%)
Gene name: GC
Sequence domains:
Structure domains: Serum Albumin; Chain A, Domain 1
Actin, alpha skeletal muscle Chain: B
Molecule details ›
Chain: B
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Structure domains:

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P212121
Unit cell:
a: 80.171Å b: 87.341Å c: 159.584Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.226 0.279