› 1ll8

Solution NMR

Structure and interactions of PAS kinase N-terminal PAS domain: Model for intramolecular kinase regulation

Released:
DOI: 10.2210/pdb1ll8/pdb
PDB entry 1ll8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ll8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ll8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation.
Amezcua CA, Harper SM, Rutter J, Gardner KH
Structure 10 1349-61 (2002)
PMID: 12377121

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188719 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PAS domain-containing serine/threonine-protein kinase Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 12.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96RG2 (Residues: 131-237; Coverage: 8%)
Gene names: KIAA0135, PASK
Sequence domains: PAS domain
Structure domains: PAS domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: molecular dynamics/simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

23 review citations

Phototropin blue-light receptors.
Christie JM. (2007)
22 more

8 mentions without citation

Structure and signaling mechanism of Per-ARNT-Sim domains.
Möglich et al. (2009)
7 more