1ky7

X-ray diffraction
2.15Å resolution

THE AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE IN COMPLEX WITH AMPHIPHYSIN FXDXF

Released:
Source organisms:
Primary publication:
Accessory protein recruitment motifs in clathrin-mediated endocytosis.
Structure 10 797-809 (2002)
PMID: 12057195

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
AP-2 complex subunit alpha-2 Chain: A
Molecule details ›
Chain: A
Length: 247 amino acids
Theoretical weight: 27.83 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P17427 (Residues: 701-938; Coverage: 25%)
Gene names: Adtab, Ap2a2
Sequence domains:
Structure domains:
Amphiphysin Chain: P
Molecule details ›
Chain: P
Length: 10 amino acids
Theoretical weight: 1.23 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49418 (Residues: 322-331; Coverage: 1%)
Gene names: AMPH, AMPH1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 40.63Å b: 73.69Å c: 41.94Å
α: 90° β: 99.74° γ: 90°
R-values:
R R work R free
0.188 0.187 0.252
Expression systems:
  • Escherichia coli
  • Not provided