1ky6

X-ray diffraction
2Å resolution

AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE IN COMPLEX WITH EPSIN DPW PEPTIDE

Released:
Source organisms:
Primary publication:
Accessory protein recruitment motifs in clathrin-mediated endocytosis.
Structure 10 797-809 (2002)
PMID: 12057195

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
AP-2 complex subunit alpha-2 Chain: A
Molecule details ›
Chain: A
Length: 247 amino acids
Theoretical weight: 27.83 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P17427 (Residues: 701-938; Coverage: 25%)
Gene names: Adtab, Ap2a2
Sequence domains:
Structure domains:
Epsin-1 Chain: P
Molecule details ›
Chain: P
Length: 7 amino acids
Theoretical weight: 765 Da
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: O88339 (Residues: 375-381; Coverage: 1%)
Gene name: Epn1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P1
Unit cell:
a: 37.302Å b: 40.896Å c: 41.611Å
α: 99.28° β: 96.42° γ: 109.47°
R-values:
R R work R free
0.186 0.186 0.245
Expression systems:
  • Escherichia coli
  • Not provided