1ktm

Solution NMR

SOLUTION STRUCTURE OF FAT DOMAIN OF FOCAL ADHESION KINASE

Released:
Source organism: Gallus gallus
Primary publication:
Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase.
Mol. Cell. Biol. 22 2751-60 (2002)
PMID: 11909967

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Focal adhesion kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.55 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00944 (Residues: 916-1053; Coverage: 13%)
Gene names: FAK, FAK1, PTK2
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 31%
Refinement method: distance geometry and torsion angle dynamics
Expression system: Escherichia coli