PDBe 1ktk

X-ray diffraction
3Å resolution

Complex of Streptococcal pyrogenic enterotoxin C (SpeC) with a human T cell receptor beta chain (Vbeta2.1)


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Exotoxin type C Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 208 amino acids
Theoretical weight: 24.38 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
  • Canonical: Q8NKX2 (Residues: 28-235; Coverage: 100%)
Gene names: speC, spyM18_0778
Sequence domains:
Structure domains:
T cell receptor beta constant 1 Chains: E, F
Molecule details ›
Chains: E, F
Length: 247 amino acids
Theoretical weight: 27.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Gene name: TRBC1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21
Unit cell:
a: 57.378Å b: 146.764Å c: 135.69Å
α: 90° β: 98.61° γ: 90°
R R work R free
0.326 0.326 0.334
Expression system: Escherichia coli