1kl9

X-ray diffraction
1.9Å resolution

Crystal structure of the N-terminal segment of Human eukaryotic initiation factor 2alpha

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 2 subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 21.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05198 (Residues: 2-183; Coverage: 58%)
Gene names: EIF2A, EIF2S1
Sequence domains: S1 RNA binding domain
Structure domains:

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P2221
Unit cell:
a: 37.28Å b: 44.2Å c: 121.42Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.198 0.233
Expression system: Escherichia coli