X-ray diffraction
1.8Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Mothers against decapentaplegic homolog 2 Chain: A
Molecule details ›
Chain: A
Length: 227 amino acids
Theoretical weight: 25.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q15796 (Residues: 241-467; Coverage: 49%)
Gene names: MADH2, MADR2, SMAD2
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: I213
Unit cell:
a: 113.7Å b: 113.7Å c: 113.7Å
α: 90° β: 90° γ: 90°
R R work R free
0.23 0.215 0.241
Expression system: Escherichia coli