X-ray diffraction
1.31Å resolution

Crystal Structure of the Guanylate Kinase-like Domain of Human CASK


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Peripheral plasma membrane protein CASK Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 20.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O14936 (Residues: 739-914; Coverage: 19%)
Gene names: CASK, LIN2
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: P3221
Unit cell:
a: 70.341Å b: 70.341Å c: 74.861Å
α: 90° β: 90° γ: 120°
R R work R free
0.188 0.186 0.212
Expression system: Escherichia coli