1kag

X-ray diffraction
2.05Å resolution

Crystal Structure of the Escherichia coli Shikimate Kinase I (AroK)

Released:

Function and Biology Details

Reaction catalysed:
ATP + shikimate = ADP + shikimate 3-phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Shikimate kinase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 173 amino acids
Theoretical weight: 19.57 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0A6D7 (Residues: 1-173; Coverage: 100%)
Gene names: JW5947, aroK, b3390
Sequence domains: Shikimate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: P21
Unit cell:
a: 35.726Å b: 63.417Å c: 67.941Å
α: 90° β: 91.27° γ: 90°
R-values:
R R work R free
0.222 0.217 0.271
Expression system: Escherichia coli BL21