X-ray diffraction
1.5Å resolution

crystal structure of RdgB- inosine triphosphate pyrophosphatase from E. coli


Function and Biology Details

Reaction catalysed:
ITP + H(2)O = IMP + diphosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
dITP/XTP pyrophosphatase Chain: A
Molecule details ›
Chain: A
Length: 221 amino acids
Theoretical weight: 23.87 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
  • Canonical: P52061 (Residues: 1-197; Coverage: 100%)
Gene names: JW2921, b2954, rdgB, yggV
Sequence domains: Ham1 family
Structure domains: Maf protein

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 78.18Å b: 78.18Å c: 80.4Å
α: 90° β: 90° γ: 90°
R R work R free
0.213 0.211 0.238
Expression system: Escherichia coli