1jwg

X-ray diffraction
2Å resolution

VHS Domain of human GGA1 complexed with cation-independent M6PR C-terminal Peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ADP-ribosylation factor-binding protein GGA1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 147 amino acids
Theoretical weight: 16.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJY5 (Residues: 1-147; Coverage: 23%)
Gene name: GGA1
Sequence domains: VHS domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Cation-independent mannose-6-phosphate receptor Chains: C, D
Molecule details ›
Chains: C, D
Length: 13 amino acids
Theoretical weight: 1.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P11717 (Residues: 2479-2491; Coverage: 1%)
Gene names: IGF2R, MPRI

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 56.146Å b: 65.77Å c: 101.426Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.226 0.261
Expression systems:
  • Escherichia coli
  • Not provided